Stefan Hippenstiel Selected Research

Tissue Plasminogen Activator (Alteplase)

1/2022

Altered fibrin clot structure and dysregulated fibrinolysis contribute to thrombosis risk in severe COVID-19.

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Stefan Hippenstiel Research Topics

Disease

32	Infections 04/2024 - 06/2004
15	Pneumonia (Pneumonitis) 01/2023 - 07/2006
14	COVID-19 01/2023 - 01/2020
10	Pneumococcal Pneumonia 01/2021 - 06/2006
9	Inflammation (Inflammations) 01/2020 - 11/2007
8	Pneumococcal Infections 01/2021 - 08/2004
7	Sepsis (Septicemia) 01/2018 - 05/2005
6	Chronic Obstructive Pulmonary Disease (COPD) 01/2023 - 03/2006
4	Edema (Dropsy) 12/2022 - 02/2003
3	Human Influenza (Influenza) 12/2022 - 01/2019
3	Critical Illness (Critically Ill) 01/2022 - 07/2009
3	Disease Progression 10/2021 - 08/2020
3	Autolysis 01/2020 - 06/2015
3	Acute Lung Injury 01/2018 - 07/2006
3	Bacterial Pneumonia 01/2018 - 01/2017
3	Emphysema 01/2016 - 01/2015
3	Ventilator-Induced Lung Injury 08/2011 - 01/2010
2	Malaria 10/2023 - 04/2021
2	Weight Loss (Weight Reduction) 11/2020 - 08/2020
2	Pulmonary Hypertension 01/2015 - 07/2006
2	Lung Injury 04/2014 - 01/2010
2	Multiple Organ Failure (MODS) 04/2014 - 08/2011
2	Body Weight (Weight, Body) 09/2013 - 02/2009
2	Respiratory Insufficiency (Respiratory Failure) 12/2010 - 01/2010
2	Atherosclerosis 03/2010 - 03/2009
2	Legionnaires' Disease (Legionnaire's Disease) 12/2008 - 05/2008
2	Septic Shock (Toxic Shock Syndrome) 11/2007 - 04/2007
2	Melanoma (Melanoma, Malignant) 04/2007 - 11/2006
1	Severe Acute Respiratory Syndrome 07/2023
1	Adenocarcinoma 11/2022
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2022
1	Hypothermia 12/2021
1	Acute malaria 04/2021
1	Communicable Diseases (Infectious Diseases) 01/2021

Drug/Important Bio-Agent (IBA)

15	CytokinesIBA 12/2021 - 05/2005
11	Proteins (Proteins, Gene)FDA Link 04/2024 - 06/2004
8	Biomarkers (Surrogate Marker)IBA 10/2023 - 01/2020
6	AdrenomedullinIBA 04/2014 - 12/2005
5	Antiviral Agents (Antivirals)IBA 04/2024 - 06/2004
4	RNA (Ribonucleic Acid)IBA 12/2022 - 01/2020
4	Streptococcus pneumoniae plY proteinIBA 01/2021 - 07/2006
4	Interleukin-8 (Interleukin 8)IBA 12/2008 - 12/2004
4	p38 Mitogen-Activated Protein KinasesIBA 11/2008 - 02/2003
3	AntibodiesIBA 04/2024 - 11/2013
3	ProteomeIBA 10/2023 - 01/2020
3	Peptides (Polypeptides)IBA 10/2021 - 04/2007
3	DNA (Deoxyribonucleic Acid)IBA 10/2018 - 07/2006
3	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2017 - 12/2004
3	Virulence Factors (Pathogenicity Factors)IBA 07/2009 - 08/2005
2	Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA 01/2023 - 12/2022
2	CalciumIBA 12/2022 - 01/2021
2	Complement System Proteins (Complement)IBA 01/2022 - 01/2020
2	Messenger RNA (mRNA)IBA 10/2021 - 08/2004
2	MicroRNAs (MicroRNA)IBA 04/2021 - 01/2016
2	EnzymesIBA 01/2021 - 05/2008
2	Transcription Factors (Transcription Factor)IBA 01/2021 - 03/2010
2	Kruppel-Like Factor 4IBA 01/2021 - 02/2013
2	InterleukinsIBA 01/2021 - 02/2013
2	Neutralizing AntibodiesIBA 11/2020 - 08/2020
2	EpitopesIBA 11/2020 - 08/2020
2	Monoclonal AntibodiesIBA 11/2020 - 08/2020
2	CV07-209IBA 11/2020 - 08/2020
2	Interleukin-6 (Interleukin 6)IBA 01/2020 - 04/2008
2	N-Acetylmuramoyl-L-alanine Amidase (Autolysin)IBA 01/2020 - 10/2015
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2020 - 05/2005
2	Phosphates (Orthophosphate)IBA 01/2018 - 08/2011
2	Toll-Like Receptors (Toll-Like Receptor)IBA 10/2015 - 11/2008
2	AlbuminsIBA 11/2013 - 05/2005
2	endolysinIBA 09/2013 - 02/2009
2	Small Interfering RNA (siRNA)IBA 02/2013 - 12/2008
2	ChromatinIBA 02/2013 - 07/2006
2	Interleukin-15 (Interleukin 15)IBA 07/2008 - 05/2007
2	Tretinoin (Retinoic Acid)FDA LinkGeneric 04/2007 - 11/2006
1	Heparin-binding EGF-like Growth Factor (HB-EGF)IBA 10/2023
1	HLA-DR Antigens (HLA-DR)IBA 10/2023
1	OsteopontinIBA 10/2023
1	VaccinesIBA 01/2023
1	ivacaftorIBA 12/2022
1	ChloridesIBA 12/2022
1	Dexamethasone (Maxidex)FDA LinkGeneric 07/2022
1	N 30IBA 07/2022
1	FibrinIBA 01/2022
1	Factor XII (Hageman Factor)IBA 01/2022
1	Tissue Plasminogen Activator (Alteplase)FDA Link 01/2022
1	Chemotactic FactorsIBA 01/2022
1	Blood Proteins (Serum Proteins)IBA 01/2022
1	KaolinIBA 01/2022
1	Carboxypeptidase B2 (Thrombin Activatable Fibrinolysis Inhibitor)IBA 01/2022
1	Plasminogen Activators (Plasminogen Activator)IBA 01/2022
1	Fibrinogen (Factor I)FDA Link 01/2022
1	BNT162 VaccineIBA 10/2021
1	HLA-C Antigens (HLA-C)IBA 10/2021
1	Proteasome Endopeptidase Complex (Proteasome)IBA 04/2021
1	Caspase 3 (Caspase-3)IBA 01/2021

Therapy/Procedure

10	Therapeutics 07/2023 - 07/2006
6	Artificial Respiration (Mechanical Ventilation) 01/2022 - 01/2010
2	Pneumonectomy (Lung Volume Reduction) 01/2016 - 01/2015
2	Mechanical Ventilators (Ventilator) 08/2011 - 12/2010
1	Critical Care (Surgical Intensive Care) 01/2022
1	Phage Therapy 12/2021